Senior Scientist, Translational Immunology*

  • Cambridge (Boston)
  • Work experience
  • Research, development, teaching
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Senior Scientist, Translational Immunology*

Become Part of the BioNTech Family.

Based in Cambridge, MA, BioNTech US serves as BioNTech’s North American headquarters and is an important part of our global effort to pioneer the development of next-generation immuno-oncology therapies. BioNTech US is a fully integrated subsidiary with a strong foundation in Europe and a focus on the development of novel neoantigen-targeted T cell therapies, complementing BioNTech’s highly innovative scientific approach and diversified pipeline of transformative cancer medicines. As a key research and clinical development hub, BioNTech US will enable BioNTech’s growing presence in the US.

BioNTech US is seeking a highly motivated Senior Scientist to join the Translational Immunology team. The team’s key goals are to understand the impact of our cutting-edge immunotherapies on the patients in our clinical trials, study the biology to understand underlying mechanisms of response and resistance, to identify biomarkers and to establish the evidence for next generation treatments. If you are excited about opportunities to work independently and have project ownership, while working on a highly collaborative team to achieve mutual goals, this may be a good role for you. As part of our multi-disciplinary team, you will work closely and collaborate with other scientists in the group, as well as with other members within the research and clinical teams. A big part of your role will include working directly with clinical samples generated during BioNTech US trials to identify biomarkers, as well as working with internal teams, external collaborators, and contract research organizations (CROs) to develop and implement a biomarker strategy.


Here, you’ll achieve greatness.

Supporting BioNTech’s R&D team in the US by:
  • Collaborate with both internal research teams and external groups/ CROs to advance translational science capabilities at BioNTech.
  • Develop Translational strategies for BioNTech sponsored clinical trials.
  • Active participation in Program Core teams and contribute to advancing the program.
  • Participate in the writing of program documents including TPP, IND, CDP and other regulatory documents.
  • Design and mentor immune assays like ELISAs, ELISPOTS, Fluorescence activated cell sorting analysis, mass cytometry and T and B cell proliferation assays.
  • Purification and characterization of PBMCs and tumor infiltrating lymphocytes from peripheral blood and lymphocytes.
  • Evaluation of T cell and B cell receptor sequences in TILS and PBMCS
  • Develop SOPS and maintain a high standard of experimentation and record keeping
  • Improvement of current processes and implementation of new technologies.

What you have to offer.

  • Ph.D., M.D., or M.D./Ph. D in Immunology with a minimum of 5 years of working experience in industry.
  • Expert in immunology and development of immune related assays.
  • Deep knowledge of T and B cell biology.
  • Prior experience working with immuno-oncology or infectious disease systems highly preferred.
  • Experience in a clinical lab and prior biomarker work highly desirable.
  • Demonstrated experience in complex problem solving.
  • Excellent organizational, communication skills and a pro-active mentality.
  • Excellent attention to detail.
  • Excellent written and oral communication skills
  • Enjoys solving challenging scientific questions in a fast pace environment
  • Independent, flexible, self-motivated, and the ability to work well with others

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
  • Medical, Dental and Vision Insurance
  • Life, AD&D, STD and LTD Insurance
  • COVID-19 Testing
  • HSA & FSA Spending Accounts
  • Health & Wellness, including free onsite gym access
  • Adoption & Surrogacy Assistance
  • Vacation and Unlimited Sick Time
  • Holidays and Floating Holidays, including discretionary winter shutdown
  • 401(K) Plan with Significant Company Match
  • Tuition Reimbursement and Professional Development
  • Commuting Assistance and free onsite parking
  • Discounted Home and Auto Insurance
  • Pet Insurance
Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.

For those who require assistance due to disability, or have questions prior to applying, please email

*BioNTech does not differentiate on the basis of gender, race, religion, color, origin, sexual orientation, disability, age and other protected status as required by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer.

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