Senior Research Associate, T Cell Immunology

  • BioNTech Careers
  • Cambridge, Massachusetts
  • Work experience
  • Research, development, teaching
  • Published: 2022-05-05
  • published till: 2022-07-31
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Senior Research Associate, T Cell Immunology

Become Part of the BioNTech Family.
Based in Cambridge, MA, BioNTech US serves as BioNTech’s North American headquarters and is an important part of our global effort to pioneer the development of next-generation immuno-oncology therapies. BioNTech US is a fully integrated subsidiary with a strong foundation in Europe and a focus on the development of novel neoantigen-targeted T cell therapies, complementing BioNTech’s highly innovative scientific approach and diversified pipeline of transformative cancer medicines. As a key research and clinical development hub, BioNTech US will enable BioNTech’s growing presence in the US.

BioNTech US is seeking a highly motivated Sr Research Associate with the goal of developing next generation neoantigen specific T cell products to be used in adoptive T cell therapy for the treatment of patients with metastatic solid tumors. As part of a multi-disciplinary team, you will work closely with the departments of T Cell Immunology, Bioinformatics, Cancer Immunology and Molecular Immunology to develop and assess the efficacy of this approach. The ideal candidate will be versed in T cell biology and have a strong technical expertise in cell-based in vitro assays as well as molecular biology. This position reports to Senior Scientist, T cell Immunology. 


Here, you’ll achieve greatness.

Supporting BioNTech’s R&D team in the US by:
• Culturing of human T cells and cancer cell lines
• Genetic manipulation of immune cell cultures
• Planning and conducting CRISPR/Cas9 screens in vitro
• Designing and executing cell-based functional assays supporting genetic screens and follow up validation studies
• Performing molecular biology techniques, including PCR
• Assessment of specificity and functionality of human T cells by multicolor flow cytometry
• Tracking and compiling results in an electronic notebook
• Assisting with the training of lab personnel
• Interactions with internal collaborators or external CMOs
• Analyzing and interpreting data, and presenting results to other scientific teams and stakeholders

What you have to offer.

• BS or MS in Immunology or related field with 2-5 years of work experience in immunotherapy or cell therapy.
• A strong interest in T cell biology and cancer immunotherapy
• Primary immune cell culture experience is required
• Knowledge and experience with genetic manipulation of cell cultures including CRISPR/Cas9 gene-editing tools is preferred
• Demonstrated experience with flow cytometry and other immune related assays is required
• Ability to work independently, as well as in a collaborative environment to meet project goals
• Excellent attention to detail • Excellent written and oral communication skills
• Enjoys solving challenging scientific questions in a fast pace environment
• Independent, flexible, self-motivated, and the ability to work well with others 

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
  • Medical, Dental and Vision Insurance
  • Life, AD&D, STD and LTD Insurance
  • HSA & FSA Spending Accounts
  • Health & Wellness, including free onsite gym access
  • Adoption & Surrogacy Assistance
  • Vacation and Unlimited Sick Time
  • Holidays and Floating Holidays, including discretionary winter shutdown
  • 401(K) Plan with Significant Company Match
  • Tuition Reimbursement and Professional Development
  • Commuting Assistance and subsidized parking
  • Discounted Home and Auto Insurance
  • Pet Insurance
Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.

For those who require assistance due to disability, or have questions prior to applying, please email

*BioNTech does not differentiate on the basis of gender, race or ethnicity, religion, color, sexual orientation or identity, disability, age and other protected statuses as given by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer. Most important – it’s a match!