Senior Research Associate, Cancer Immunology

  • BioNTech Careers
  • Cambridge, Massachusetts
  • Work experience
  • Research, development, teaching
  • Published: 15.09.2022
  • published till: 30.11.2022
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Senior Research Associate, Cancer Immunology

BioNTech is a Germany-based biotechnology company with U.S. offices in Cambridge, MA and Gaithersburg, MD, that focuses on developing cancer therapeutics, including individualized immunotherapy, as well as vaccines for infectious diseases, including COVID-19. The company’s oncology pipeline contains several classes of drugs, including mRNA-based drugs to encode antigens, neoantigens, cytokines, and antibodies; cell therapies; bispecific antibodies; and small-molecule immunomodulators. BioNTech is partnered with several large pharmaceutical companies, including Roche, Eli Lilly, Pfizer, Sanofi, and Genmab. Comirnaty (COVID-19 vaccine) is its first commercialized product.

BioNTech US is seeking a highly-motivated Senior Research Associate to enable the development of adoptive T cell therapy products. You will help with the implementation of a robust TCR discovery and characterization pipeline. You will also help evaluate T cell modifications and combination therapies to enhance our TCR T cell products. As part of a multi-disciplinary team, you will work closely with the departments of T cell therapy and biochemistry to develop and assess the efficacy of our T cell products.

Here, you’ll achieve greatness.


 
Responsibilities:
  • Culturing and engineering of human T cells
  • TCR sequencing and characterization of new TCRs
  • Perform functional and phenotypic characterization of TCR engineered T cells by multicolor flow cytometry, MSD, and cytotoxicity assays
  • Executing cell-based functional assays to evaluate T cell modifications and combination therapies in vitro and in vivo
  • Tracking and compiling results in an electronic notebook
  • Assisting with the training of lab personnel
  • Presenting results to other scientific teams

What you have to offer.


Requirements:
  • BS or MS in Immunology or related discipline, plus at least 1-3 years of relevant work experience
  • A strong interest in T cell biology and cancer immunotherapy
  • Primary cell culture experience
  • Demonstrated experience with flow cytometry and other immune related assays
  • Ability to work independently, as well as in a collaborative environment to meet project goals
  • Excellent attention to detail
  • Excellent written and oral communication skills
  • Enjoys solving challenging scientific questions in a fast pace environment
  • Independent, flexible, self-motivated, and the ability to work well with others

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
  • Medical, Dental and Vision Insurance
  • Life, AD&D, STD and LTD Insurance
  • HSA & FSA Spending Accounts
  • Health & Wellness, including free onsite gym access
  • Adoption & Surrogacy Assistance
  • Vacation and Unlimited Sick Time
  • Holidays and Floating Holidays, including discretionary winter shutdown
  • 401(K) Plan with Significant Company Match
  • Tuition Reimbursement and Professional Development
  • Commuting Assistance and subsidized onsite parking
  • Discounted Home and Auto Insurance
  • Pet Insurance
Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.

For those who require assistance due to disability, or have questions prior to applying, please email careers@join-us.biontech.de.

*BioNTech does not differentiate on the basis of gender, race or ethnicity, religion, color, sexual orientation or identity, disability, age and other protected statuses as given by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer. Most important – it’s a match!


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