Scientist, Computational Biology

  • Cambridge, Massachusetts
  • Work experience
  • Research, development, teaching
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Scientist, Computational Biology

Become Part of the BioNTech Family.

Based in Cambridge, MA, BioNTech US serves as BioNTech’s North American headquarters and is an important part of our global effort to pioneer the development of next-generation immuno-oncology therapies. BioNTech US is a fully integrated subsidiary with a strong foundation in Europe and a focus on the development of novel neoantigen-targeted T cell therapies, complementing BioNTech’s highly innovative scientific approach and diversified pipeline of transformative cancer medicines. As a key research and clinical development hub, BioNTech US will enable BioNTech’s growing presence in the US.

BioNTech US is seeking an exceptional Scientist to join our Computational Biology team!


Here, you’ll achieve greatness.

Primary responsibilities include:
  • Computational analysis of mass spectrometry data with the goals of:
    • Discovering novel cancer therapy targets (especially for vaccines and cellular therapies like TCR-T and CAR-T)
    • Evaluating/designing new algorithms for spectral interpretation
  • Investigation of new hypotheses and target concepts (e.g "dark matter", cancer-specific PTMs, translational errors, etc.) using genomics and proteomics data
  • Data-driven design of mRNA vaccines for infectious disease
  • Development of deep-learning based methods for epitope mapping and prediction
  • Collaboration with diverse scientific teams (especially proteomics bench scientists) towards the goal of bringing new targets into the clinic; leading/co-leading projects in a multifunctional, matrixed team setting

What you have to offer.

  • PhD in Computational Biology or related field
  • Expertise in proteomics and mass spectrometry
  • Proficiency with Python or R
  • Experience working in Linux environment
  • Strong communication and organizational skills
  • Preferred:  Understanding of immunology, especially T cell biology
  • Preferred:  Understanding of cancer biology
Preferred:  Understanding of structural biology

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
  • Medical, Dental and Vision Insurance
  • Life, AD&D, STD and LTD Insurance
  • HSA & FSA Spending Accounts
  • Health & Wellness, including free onsite gym access
  • Adoption & Surrogacy Assistance
  • Vacation and Unlimited Sick Time
  • Holidays and Floating Holidays, including discretionary winter shutdown
  • 401(K) Plan with Significant Company Match
  • Tuition Reimbursement and Professional Development
  • Commuting Assistance and subsidized parking
  • Discounted Home and Auto Insurance
  • Pet Insurance
Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.

For those who require assistance due to disability, or have questions prior to applying, please email

*BioNTech does not differentiate on the basis of gender, race or ethnicity, religion, color, sexual orientation or identity, disability, age and other protected statuses as given by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer. Most important – it’s a match!