Scientist, Cancer Immunology*

  • Cambridge, Massachusetts
  • Work experience
  • Research, development, teaching
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Scientist, Cancer Immunology*

Become Part of the BioNTech Family.

Based in Cambridge, MA, BioNTech US serves as BioNTech’s North American headquarters and is an important part of our global effort to pioneer the development of next-generation immuno-oncology therapies. BioNTech US is a fully integrated subsidiary with a strong foundation in Europe and a focus on the development of novel neoantigen-targeted T cell therapies, complementing BioNTech’s highly innovative scientific approach and diversified pipeline of transformative cancer medicines. As a key research and clinical development hub, BioNTech US will enable BioNTech’s growing presence in the US.

We are seeking a highly motivated Scientist to join BioNTech’s Cancer Immunology team focused on novel T cell receptor (TCR) T cell therapies targeting solid tumors at our Cambridge, MA location. Specifically, this role will be responsible for evaluating combination therapies and T cell modifications to enhance our TCR T cell therapies. As part of a multi-disciplinary team, you will work closely with other Cell Therapy teams at our US and Germany BioNTech sites.


Here, you’ll achieve greatness.

Supporting BioNTech’s R&D team in the US by:
  • Culturing of human T cells and cancer cell lines
  • Engineering of T cells using viral and non-viral methods
  • Performing functional and phenotypic characterization of engineered T cells by multicolor flow cytometry, MSD, and cytotoxicity assays
  • Designing and executing cell-based functional assays to evaluate T cell modifications and combination therapies in vitro
  • Developing in vivo models to study combination therapies with our TCR T cell therapy
  • Tracking and compiling results in an electronic notebook
  • Interacting with internal collaborators and external CROs
  • Assisting with the training of lab personnel
  • Presenting results to other scientific teams

What you have to offer.

  • PhD in Immunology, Biomedical Sciences, or a closely related field with 0-3 years of relevant experience
  • Strong skills in cell culture and aseptic techniques, as well as experience with the cultivation of primary human cells
  • Experience in immunological techniques such as activation of T cells, viral vector generation, T cell transduction, and electroporation
  • Experience with multicolor flow cytometry and assay development
  • Experience with primary T cell-based assays (e.g. ELISPOT, MSD, cytotoxicity)
  • Experience with in vivo mouse tumor models
  • Comfortable in a fast-paced environment and able embrace change, while working to produce key deliverables in accordance with project timelines
  • Strong verbal and written communication skills and ability to communicate results to a diverse cross-functional audience
  • Proactive, self-motivated team player with strong interpersonal skills, appropriate sense of urgency and the ability to work independently

Benefits for you.

BioNTech US is committed to the well being of our team members and offers a variety of benefits supporting our diverse employee base. Salaried/Position-Targeted Hourly Employees working 30+ hours per week are eligible for our comprehensive benefits package. Benefits include but are not limited to:
  • Medical, Dental and Vision Insurance
  • Life, AD&D, STD and LTD Insurance
  • HSA & FSA Spending Accounts
  • Health & Wellness, including free onsite gym access
  • Adoption & Surrogacy Assistance
  • Vacation and Unlimited Sick Time
  • Holidays and Floating Holidays, including discretionary winter shutdown
  • 401(K) Plan with Significant Company Match
  • Tuition Reimbursement and Professional Development
  • Commuting Assistance and free onsite parking
  • Discounted Home and Auto Insurance
  • Pet Insurance
Plus more benefits that will be shared upon hire!

Have we kindled your pioneering spirit?

Then apply now for our location Cambridge (Boston) and simply send us your application documents using our online form.

For those who require assistance due to disability, or have questions prior to applying, please email

*BioNTech does not differentiate on the basis of gender, race or ethnicity, religion, color, sexual orientation or identity, disability, age and other protected statuses as given by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer. Most important – it’s a match!