Director* Translational Sciences

  • Mainz
  • Research, development, teaching
  • Published: 04.01.2022
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Become a member of the BioNTech Family!

As a part of our team of more than 2.500 pioneers, you will play a key role in developing solutions for some of the most crucial scientific challenges of our age. Within less than a year, we were able to develop our COVID-19 mRNA vaccine following the highest scientific and ethical standards – writing medical history.
 
We aim to reduce the suffering of people with life-changing therapies by harnessing the potential of the immune system to develop novel therapies against cancer and infectious diseases. While doing so, we are guided by our three company values: united, innovative, passionate. Get in touch with us if you are looking to be a part of creating hope for a healthy future in many people's lives.

Director Translational Sciences

Your main responsibilities are:
  • As Associate Director / Director Translational scientist lead in assigned programs, responsible for developing and executing the biomarker strategy from exploratory early studies to ph 2/3 studies with registrational intend, in alignment with clinical development objectives
  • Responsible for bridging preclinical experimental data to translational strategies in the assigned programs to deeply integrate the mechanism of action to the clinical development plan (target engagement, pharmacodynamics endpoints, patient selection) and correlate with clinical outcomes
  • Providing scientific, technologic and strategic guidance and hands-on contribution to biomarker programs accompanying clinical trials to drive the company´s R&D programs; experience in CDx development is a plus
  • Coordinating Biomarker related program activities with internal and external stakeholders and driving integration of services, technologies, and capabilities to ensure reaching of program goals
  • Provides state of the art biomarker input in regulatory documents (clinical study reports, IND, BLA documentation)
  • Analyzes, interprets and presents clinical biomarker data and draws scientifically valid conclusions that support and enable decision making

What you have to offer.

  • Ph.D. or PhD/MD in Immunology, molecular biology, pathology or related discipline with scientific background in Oncology or Immuno-Oncology
  • At least two years of clinical development experience as biomarker project lead in the biotech/pharmaceutical industry
  • Experienced in bridging preclinical experimental data to translational biomarker strategies to deeply integrate the mechanism of action in the clinical development plan (target engagement, pharmacodynamics endpoints, patient selection) and correlate with clinical outcomes.
  • Scientific accomplishments as evidenced by publications in peer reviewed journals and as speaker of conferences.
  • Therapeutic knowledge in the areas of oncology and immune-oncology
  • Experienced in working within interdisciplinary cross-functional teams with other key development functions (clinical lead, regulatory, biostatistics, operations and clinical pharmacology).
  • Experienced with relevant tools and procedures for biomarker assessments (e.g. Bioassays).  Experience in companion diagnostics development is a plus.
  • A genuine interest and understanding of the science supporting the development programs. Confident to discuss and present scientific and translational aspects of immunotherapy drug development.
  • Comfortable in working in a matrix environment (global/cross-functional), including contributing to establishing clarity and structures and driving state of the art collaborations with external academic and industry partners.

Benefits for you.

  • Company Pension Scheme
  • Childcare
  • Jobticket
  • Company Bike
  • Leave Account
  • Fitness Courses
  • Mobile Office
  • Special Vacation
... and much more.

Have we kindled your pioneering spirit?

Then apply now for our location Mainz and simply send us your application documents using our online form.

If you have any further questions, our Talent Acquisition Team will be happy to answer them on + 49 (0) 6131-9084-1291 
(monday-friday, from 12 noon to 4 pm).

Job-ID 4131 (please indicate for inquiries)

We look forward to your application!

*BioNTech does not differentiate on the basis of gender, race or ethnicity, religion, color, sexual orientation or identity, disability, age and other protected statuses as given by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer. Most important – it’s a match!

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