Associate Director* Clinical Pharmacology

  • Mainz
  • Research, development, teaching
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Become a member of the BioNTech Family!

As a part of our team of more than 1.500 pioneers, you will play a key role in developing solutions for some of the most crucial scientific challenges of our age: Amongst multiple programs in the pipeline, we are conducting research on a Covid-19 vaccine in our project “Lightspeed” based on our mRNA-technologies. Furthermore, we are pioneers in the development of individualized cancer therapies and in the combat against other diseases.
 
We aim to achieve life-changing successes for patients by being innovative, passionate and united,so get in touch with us if you are looking to be a part of creating hope for a healthy future in many people´s lives.

Associate Director* Clinical Pharmacology

At BioNTech, you will be a key part of the PK/PD clinical pharmacology group. Performing analysis, interpretation and reporting of clinical pharmacokinetic data for the clinical development of BNT assets. Your main responsibilities are:
  • Performs analysis, interpretation and reporting of clinical pharmacokinetic data
  • Executes PKPD, exposure response and translational modeling and quantitative pharmacology activities to achieve mechanistic understanding of novel drug candidates, and support optimal dose and dosing schedule decisions
  • Plans, designs, executes and reports program-specific clinical pharmacology studies (e.g. assessment of QT, food effect, ADME, DDI strategy, special populations, etc.) to support development and rapid registration of BioNTech products, by working cross-functionally with Translational Sciences Lead, Clinical Research, Biomarker operations specialists and other partners
  • Partners with cross functional experts for the design and data analysis/interpretation of pharmacokinetic (PK), toxicokinetic and pharmacodynamics (PD) aspects of preclinical studies
  • Provides state of the art clinical pharmacology input in regulatory documents (CSP related PK endpoints, SoA, IND, final study reports, NDA)
  • Provides translational PK expertize and representation at global health authority meetings

What you have to offer.

  • Ph.D. in pharmaceutics, pharmacokinetics, pharmacology, or related discipline with scientific and clinical background in Oncology and/or infectious diseases
  • Previous experience in the biotechnology or pharmaceutical industry including a good understanding of early and late drug development process from IND through NDA/BLA
  • Direct experience in leading clinical pharmacology activities in drug development programs
  • Experience in translational research and its application to cancer drug development, including PKPD, exposure response and translational modeling activities to support optimal dose and dosing schedule decisions
  • Strong research background and interest in understanding PK data in the context of complex biology
  • Strong documentation and organizational skills
  • Proven ability to work independently and be self-motivated
  • Excellent communication and presentation skills to efficiently relay information to project teams and other key stakeholders
  • Previous experience working in a matrix environment is preferred
  • Proficiency in English (written and spoken)

Benefits for you.

  • Company Pension Scheme
  • Childcare
  • Jobticket
  • Company Bike
  • Leave Account
  • Fitness Courses
  • Mobile Office
  • Special Vacation
... and much more.

Have we kindled your pioneering spirit?

Then apply now for our location Mainz and simply send us your application documents using our online form.

If you have any further questions, Reece Freeman will be happy to answer them on + 49 (0) 6131-9084-1211 (monday-friday, from 12 noon).

*BioNTech does not differentiate on the basis of gender, race, religion, color, origin, sexual orientation, disability, age and other protected status as required by applicable law. We are committed to creating a diverse environment and are proud to be an equal opportunity employer.

BioNTech - As unique as you

https://biontech.de